Graves’ Disease and Marine Lenhart Syndrome: A Rare Clinical Presentation
Autor: | Renata Maksoud Bussuan, Adriana Andrade de Sousa, Larissa Bianca Paiva Cunha de Sá, Adriana Farias Araújo, Fernanda Cardia Martins Ribeiro, Ana Luísa Conceição de Jesus, Alberto Krayyem Arbex, Jonathan Mwambire, Aluysio Leal Júnior, Larissa Alves Ruas |
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Rok vydání: | 2019 |
Předmět: |
Thyroid nodules
endocrine system medicine.medical_specialty endocrine system diseases business.industry Thyroid disease Graves' disease Thyroid Disease medicine.disease Dermatology eye diseases Pathogenesis medicine.anatomical_structure Autoimmune Process medicine General Earth and Planetary Sciences Presentation (obstetrics) business General Environmental Science |
Zdroj: | Health. 11:1169-1176 |
ISSN: | 1949-5005 1949-4998 |
Popis: | The aim of this study is to review and discuss the clinical features and treatment options for the Marine-Lenhart syndrome, an uncommon thyroid disturb. The methodology adopted was a bibliographic research. The results of this study show that different mechanisms are implicated in the pathogenesis of Graves’ disease and in the nodular formation of thyroid tissue with functional autonomy. Graves’ disease is caused by an autoimmune process that involves the entire thyroid gland and is characterized by the presence of TSH receptor stimulating antibodies. The present study concludes that caution should be exercised in interpreting thyroid disease in Graves’ disease. The treatment of thyrotoxicosis requires high doses of oral drugs. Relapsing antithyroid therapy occurs soon after oral antithyroid therapy is discontinued. This presentation should alert the physician about the existence of toxic nodules, and about the possibility of a Marine-Lenhart Syndrome. |
Databáze: | OpenAIRE |
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