Preparation of the diastereomerically pure 2S-hydroxy derivative of dihydrolevoglucosenone (cyrene)

Autor:	B. T. Sharipov, Liliya Kh. Faizullina, A. N. Davydova, Farid A. Valeev
Rok vydání:	2019
Předmět:	chemistry.chemical_compound Stereospecificity chemistry 010405 organic chemistry Hydroxy derivative Organic chemistry Alcohol Epimer General Chemistry 010402 general chemistry 01 natural sciences 0104 chemical sciences
Zdroj:	Mendeleev Communications. 29:200-202
ISSN:	0959-9436
DOI:	10.1016/j.mencom.2019.03.029
Popis:	Diastereomerically pure levoglucosenone alcohol, synthesized from levoglucosenone, upon hydrogenation on Raney Ni or Pd/BaSO4 undergoes epimerization at C2 atom caused by formation of cyrene by-product and its subsequent non-specific reduction. A microbiological stereospecific technique using baker's yeast (Saccharomyces cerevisiae) has been developed levoglucosenone for cyrene reduction into cyrene alcohol and also applied to reduce 4-alkoxy and 4-benzyloxy derivatives of cyrene.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4a914cad09fcc8731b297d4926c161c4 https://doi.org/10.1016/j.mencom.2019.03.029 Zobrazit plný text záznamu Full Text from ScienceDirect