Development of CAR-T Therapies: Case Histories of Significant Medical Advances
Autor: | Amar Bhidé, Srikant M. Datar |
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Rok vydání: | 2021 |
Předmět: | |
Zdroj: | SSRN Electronic Journal. |
ISSN: | 1556-5068 |
Popis: | In 2017, the US Food and Drug Administration (FDA) approved an immunotherapeutic treatment, called CAR-T therapy, for two kinds of blood cancers — acute leukemia (ALL) and a lymphoma. We describe: 1) how CAR-T therapies (are believed to) work; 2) foundational advances and discoveries (through the 1980s); 3) the development of CAR-T therapy (during and after the 1990s); and 4) prospects for the 2020s. |
Databáze: | OpenAIRE |
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