Bone mineral content in postmenopausal women, calcium intake early in life, and estrogen therapy
| Autor: | Virginia A. Clark, I F Hunt, Marcelle I. Cedars, Howard L. Judd, N J Murphy, Ben L Browdy |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
medicine.medical_specialty
Nutrition and Dietetics Bone density Bone disease medicine.drug_class business.industry Endocrinology Diabetes and Metabolism Osteoporosis Estrogen therapy chemistry.chemical_element Calcium medicine.disease Menopause Endocrinology medicine.anatomical_structure chemistry Estrogen Internal medicine medicine Cortical bone business |
| Zdroj: | Nutrition Research. 10:1061-1071 |
| ISSN: | 0271-5317 |
| DOI: | 10.1016/s0271-5317(05)80328-8 |
| Popis: | A cross-sectional study of the relationship of calcium intake and estrogen therapy (ET) to cortical bone mineral content/bone width (BMC/BW) was conducted in 129 postmenopausal "free-living" women in California. Diet was assessed by frequency questionnaire, ET by interview, and BMC by single-photon absorptiometry. Women with adequate ET (defined as ≥0.625 mg conjugated equine estrogen/d for >20 d/mo beginning within 3 y after menopause and continuing >3 y) were compared to those who had not received ET. Calcium intakes early in life (15 to 30 y of age) were predictive of BMC/BW only in women with adequate ET. Calcium intakes later in life were not predictive regardless of ET. In women who had both adequate ET and early calcium intakes >500 mg/d, BMC/BW could be expected to fall below the "fracture threshold" (0.58 g/cm 2 ) about 17 y later than in all other subjects. Adequate early calcium intakes may contribute to bone formation and, since ET reduces bone loss, the 2 strategies combined may be more effective in maintaining BMC than either one alone. |
| Databáze: | OpenAIRE |
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