Hypergammaglobulinemia in an SIV-Infected Rhesus Macaque with a B-cell neoplasm with plasma cell differentiation
| Autor: | Brigitte E Sanders-Beer, Lowrey Rhodes, Joshua A. Kramer, Keith G. Mansfield, Yvette Edghill Spano |
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| Rok vydání: | 2011 |
| Předmět: |
Pathology
medicine.medical_specialty General Veterinary biology Cellular differentiation Hypergammaglobulinemia Hyperglobulinemia Simian immunodeficiency virus Plasma cell biology.organism_classification medicine.disease Immunoglobulin light chain medicine.disease_cause Rhesus macaque medicine.anatomical_structure hemic and lymphatic diseases Plasma cell differentiation medicine Animal Science and Zoology |
| Zdroj: | Journal of Medical Primatology. 40:200-204 |
| ISSN: | 0047-2565 |
| Popis: | An SIV-infected rhesus macaque presented with anemia, hypercalcemia, and hyperglobulinemia. Neoplastic round cells with plasma cell morphology infiltrated multiple organs and stained immunohistochemically positive for CD45, MUM1/IRF4, CD138, VS38C, and Kappa light chain and variably positive for CD20 and CD79a; consistent with a B-cell neoplasm with plasma cell differentiation. |
| Databáze: | OpenAIRE |
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