Preprotachykinin gene expression in goldfish brain

Autor:	Xinwei Lin, H Saied, Pierre Peyon, Richard E. Peter
Rok vydání:	2000
Předmět:	Preprotachykinin Physiology Sequence analysis Tachykinin peptides Biology Biochemistry Molecular biology Cellular and Molecular Neuroscience Endocrinology nervous system Complementary DNA Gene expression heterocyclic compounds sense organs Northern blot Gene Peptide sequence
Zdroj:	Peptides. 21:225-231
ISSN:	0196-9781
DOI:	10.1016/s0196-9781(99)00190-4
Popis:	Recently, we described the complete nucleotide sequence of γ-preprotachykinin (γ-PPT) mRNA and the deduced amino acid sequence of the precursor on the basis of molecular cloning and sequence analysis of cDNA from goldfish brain. In the present study, γ-PPT gene expression in the brain of goldfish was examined using quantitative Northern blot analysis. The results showed that the γ-PPT gene is highly but differentially expressed in the olfactory bulbs, hypothalamus, and posterior brain regions. There are sexual dimorphism and seasonal variations in γ-PPT gene expression. In addition, the postprandial changes in γ-PPT gene expression in the olfactory bulbs and hypothalamus suggest that tachykinin peptides are involved in regulation of feeding behavior in goldfish.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4a681f2c9d24cd19396ad1f85cd8fff7 https://doi.org/10.1016/s0196-9781(99)00190-4 Zobrazit plný text záznamu Full Text from ScienceDirect