Endoscopic Diagnosis of Bronchial Tuberculosis in Pulmonary Tuberculosis Patients with Different HIV Status

Autor: M. V. Sinitsyn, S. V. Bykov, M. N. Reshetnikov, I. S. Aralova, A. G. Antipov
Rok vydání: 2022
Předmět:
Zdroj: Tuberculosis and Lung Diseases. 100:28-33
ISSN: 2542-1506
2075-1230
DOI: 10.21292/2075-1230-2022-100-7-28-33
Popis: The objective: to compare the effectiveness of endoscopic diagnosis of bronchial tuberculosis in pulmonary tuberculosis patients with different HIV status.Subjects and Methods. The data obtained during tracheobronchoscopy in 371 respiratory tuberculosis patients from 2018 to 2020 were retrospectively studied. The indication for bronchoscopy was the presence of clinical and radiological symptoms characteristic of bronchial tuberculosis in a pulmonary tuberculosis patient. All patients were divided into two groups: HIV+ and HIV-.Results. In pulmonary tuberculosis patients with clinical and radiographic findings characteristic of bronchial tuberculosis, the frequency of endoscopic confirmation of bronchial tuberculosis in HIV+ Group was 57/71 (80.3%), in HIV- Group – 138/300 (46.0%), p < 0.01; χ2 = 27.06.Most often, in HIV-positive patients, the infiltrative form of bronchus tuberculosis was detected – 27 (47.4%) patients, and the fistulous form – 23 (40.4%) patients, bronchial lesions in HIV negative tuberculosis patients were mainly infiltrative – 94 (68.1%) or ulcerative – 24 (17.4%).The frequency of microbiological detection of the causative agent of tuberculosis increased when bronchobiopsy was performed versus sputum microscopy, especially in HIV negative tuberculosis patients (from 39.9 to 91.3%), and among HIV positive patients from 15.7 to 47.4%.
Databáze: OpenAIRE