Synthesis, Characterization and Antiviral Activity of Chrysin Derivatives

Autor:	P. Poorna, K. Rama Krishna, M. Suri Appa Rao
Rok vydání:	2021
Předmět:	General Chemistry
Zdroj:	Asian Journal of Chemistry. 33:2965-2971
ISSN:	0975-427X 0970-7077
Popis:	In this work, the isolation of chrysin (1), which is a significant constituent from hexanes concentrate of Derris scandens is reported. A progression of new 1,2,3-triazole subsidiaries of chrysin were planned, combined and assessed for their antiviral movement against newcastle disease virus (NDV) and blue tongue virus (BTV) cell lines. These synthetic derivatives have indicated great antiviral action. All the synthesized compounds (3a to 3g) were distinguished by using nuclear magnetic resonance (NMR) and mass spectroscopic techniques. Among derivatives, 3a, 3e, 3f and 3g displayed conspicuous action against NDV, then again compounds 3a, 3b, 3c, 3e, 3f and 3g showed a remarkable action against BTV than chrysin.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4a44b59dada97f454bc696a1631b5a3d https://doi.org/10.14233/ajchem.2021.23400 Zobrazit plný text záznamu