Total Synthesis of the Slime Mold Alkaloids Arcyroxocin A and B

Autor:	Gregor Wille, Kirsten Zeitler, Guido Mayer, Michael Brenner, Wolfgang Steglich
Rok vydání:	2010
Předmět:	Pigment Oxidative cyclization Chemistry Stereochemistry visual_art Organic Chemistry visual_art.visual_art_medium Slime mold Total synthesis Organic chemistry Oxidative phosphorylation Ring (chemistry) Catalysis
Zdroj:	Synthesis. 2011:330-336
ISSN:	1437-210X 0039-7881
DOI:	10.1055/s-0030-1258340
Popis:	The synthesis of the slime mold pigments arcyroxocin A and Bis described. The key step in the synthesis is the oxidative ring closureof an N-protected 3-(4-hydroxyindol-3-yl)-4-indol-3-ylmaleimidewith DDQ/PPTS, which affords exclusively the desired arcyroxocinderivative. Attempts to obtain the arcyroxocin system from a 3-(4-hydroxyindolyl)-4-(2-oxoindolinyl)maleimideprecursor were less successful and led to oxidative formation ofa spiroindoline compound.
Databáze:	OpenAIRE
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