Microwave-accelerated Solvent and Catalyst Free Synthesis of 3-Indolylhydroquinones

Autor: T. Swamy, K. Premalatha, Jhillu S. Yadav, K. Shiva Shankar, B. V. Subba Reddy
Rok vydání: 2008
Předmět:
Zdroj: Bulletin of the Korean Chemical Society. 29:1418-1420
ISSN: 0253-2964
DOI: 10.5012/bkcs.2008.29.7.1418
Popis: The 3-indolylbenzoquinone nucleus is present in various biologically active natural products such as asterriquinones. 1 The asterriquinones and demethylasterriquinones (Figure 1) have recently been isolated from a wide range of fungi, including Aspergillus terreus, Chaetomium sp. and Pseudomassaria sp. 2 They exhibit a wide spectrum of biological activities including antitumor properties and are inhibitors of HIV reverse transcriptase. 3 Asterriquinone A1 has been shown to arrest the cell cycle in G1 and promote apoptotic cell death. 4 Recently, asterriquinone has also been reported
Databáze: OpenAIRE