ChemInform Abstract: Controlled Epimerization of Indolo[2,3-a]quinolizidine Derivatives: An Efficient Total Synthesis of (.+-.)-Tacamonine

Autor: Kimmo Karinen, Mauri Lounasmaa, Arto Tolvanen, David Din Belle
Rok vydání: 2010
Předmět:
Zdroj: ChemInform. 29
ISSN: 1522-2667
0931-7597
Popis: Base-catalysed epimerization of the easily accessible trans ester 3 at C-1 gives rise in good yield to the seemingly less stable cis ester 2, which can be converted into the indole alkaloid tacamonine (1) in three steps.
Databáze: OpenAIRE