The yicJI metabolic operon of Escherichia coli is involved in bacterial fitness
| Autor: | Gaëlle Porcheron, Maryline Répérant, Géraldine Rouquet, Philippe Gilot |
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| Rok vydání: | 2011 |
| Předmět: |
2. Zero hunger
Genetics Regulation of gene expression 0303 health sciences 030306 microbiology Operon Promoter Biology biology.organism_classification medicine.disease_cause Microbiology Enterobacteriaceae 03 medical and health sciences medicine bacteria L-arabinose operon Molecular Biology Gene Escherichia coli 030304 developmental biology Palindromic sequence |
| Zdroj: | FEMS Microbiology Letters. 319:180-186 |
| ISSN: | 0378-1097 |
| Popis: | The yicJI operon of the common genetic backbone of Escherichia coli codes an α-xylosidase and a transporter of the galactosides--pentoses--hexuronides:cation symporter family. In the extraintestinal pathogenic E. coli strain BEN2908, a metabolic operon (frz) of seven genes is found downstream of the yicI gene. It was proved that frz promotes bacterial fitness under stressful conditions. During this work, we identified a motif containing a palindromic sequence in the promoter region of both the frz and the yicJI operons. We then showed that these two operons are cotranscribed, suggesting a functional relationship. The phenotypes of frz and yicJI deletion mutants were compared. Our results showed that although the yicJI operon is not essential for the life of E. coli, it is necessary for its fitness under all the growth conditions tested. |
| Databáze: | OpenAIRE |
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