Diplopia and Acute Sixth Nerve Palsy in Hypervitaminosis A – A Case Report and a Review Literature

Autor:	Mumtahina Setu, Sayeeda Anwar, Akm Matiur Rahman, Mohsin, Azimul Haque, Manisha Bannerjee
Rok vydání:	2012
Předmět:	Vitamin Diplopia business.industry General Medicine medicine.disease Hypervitaminosis A Sixth nerve palsy Acute toxicity chemistry.chemical_compound chemistry Accidental Anesthesia medicine Ingestion medicine.symptom business Chronic toxicity
Zdroj:	Bangladesh Journal of Child Health. 35:36-37
ISSN:	2408-8315 0257-3490
Popis:	The daily recommended dose of vitamin A is 500 mcg in adult, 250-350 mcg in children and 600 mcg in pregnant woman2. Acute toxicity of vitamin A occurs within a few hours or days after ingestion of very large amount as a result of accidental overdose or inappropriate therapy. Children often got attracted to vitamin A capsule due to their attractive colours thus accidental ingestion may occur frequently. The estimated toxic dose is about 25,000 IU/kg. A single dose of >1 million units of vitamin A can also cause acute toxicity3. Chronic toxicity in older children and adults usually develop after doses of >50,000IU/day taken for months4. Both acute and chronic toxicity usually cause headache due to increased intracranial pressure. Here we wish to report this case of a 11 years old girl presented with diplopia and 6th nerve palsy, 24 hours after accidental ingestion of a large dose of vitamin A.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4a18a4cbe5dda83efcae9f6dec90f6f9 https://doi.org/10.3329/bjch.v35i1.10372 Zobrazit plný text záznamu