Asymmetric Organocatalytic Michael Addition-Cyclization Cascade Reaction of Nitroalkanes with o-Hydroxycinnamaldehydes

Autor:	Sung-Gon Kim, Kwang‐Su Choi
Rok vydání:	2012
Předmět:	Diphenylprolinol Chemistry Organic Chemistry Enantioselective synthesis Ether Catalysis chemistry.chemical_compound Cascade reaction Organocatalysis Michael reaction medicine Organic chemistry Physical and Theoretical Chemistry medicine.drug
Zdroj:	European Journal of Organic Chemistry. 2012:1119-1122
ISSN:	1434-193X
Popis:	A catalytic enantioselective Michael addition–cyclization reaction of nitroalkanes with o-hydroxycinnamaldehydes has been established by using a diphenylprolinol TMS ether as an organocatalyst. The reaction afforded the corresponding 4-substituted chroman-2-ols in excellent yields with high levels of enantioselectivities (95 to >99 % ee).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4a0fac57db97ff100183baf12620dbcd https://doi.org/10.1002/ejoc.201101794 Zobrazit plný text záznamu Plný text