Bovine papilloma: aetiology, pathology, immunology, disease status, diagnosis, control, prevention and treatment: a review

Autor: Adole Jolly Amoche, Najume Dogowar Giginya Ibrahim, Idoko Sunday Idoko, Chioma Inyang Aneke, Iniobong Chukwuebuka Ikenna Ugochukwu, Celestine Ibe O. Njoku, Wayuta Philip Mshiela, Richard Emmanuel Ede, N. A. Sani, A. K. B. Sackey
Rok vydání: 2018
Předmět:
Zdroj: Comparative Clinical Pathology. 28:737-745
ISSN: 1618-565X
1618-5641
DOI: 10.1007/s00580-018-2785-3
Popis: Bovine papillomavirus (BPV) induces diseases of economic and veterinary importance leading to significant economic losses to livestock owners such as leather depreciation and mortality when it progresses to neoplasms. BPV affects the spinosum and granulosum layers of the skin causing warts. There are many reportage of BPV infection in domestic animals such as cattle, birds and wild animals such as tapir, giraffe, antelope and zebras. It also causes equine sarcoids in horses and donkeys. Gross lesions seen are mainly benign papillomas which most times regress but occasionally persist and progress to malignancy of the urinary bladder and upper alimentary tract leading to Enzootic haematuria. Equine sarcoids could be of the occult, nodular or verrucous types. Due to the ability to BPV to cause cancers, haematuria and skin pathologies, diagnosis of this infection has attracted huge interests. Diagnostic techniques include clinical examination, histopathology, polymerase chain reaction (PCR) Southern blot, dot blot, reverse blot, in situ hybridization and immunohistochemistry. All the aforementioned have been very helpful in the diagnosis of BPV. In conclusion, this review focused on the aetiology, viral structure pathogenicity, transmission, macroscopic and microscopic pathology, pathogenesis, immunology, gene products, prevention, treatment and control of this virus in affected animal species.
Databáze: OpenAIRE
Externí odkaz: