Total synthesis of 2'-O-methyl-β-l-arabinosyluridine and reassignment the nucleoside from penicillium sp. as 2'-O-methyl-β-l-uridine

Autor:	Xueping Tao, Haixin Ding, Banpeng Cao, Jiang Bai, Qiang Xiao, Yiyuan Peng, Chunyang Shen, Ruchun Yang
Rok vydání:	2020
Předmět:	biology 010405 organic chemistry Stereochemistry Chemistry Total synthesis Plant Science biology.organism_classification 01 natural sciences Biochemistry Uridine 0104 chemical sciences 010404 medicinal & biomolecular chemistry chemistry.chemical_compound Penicillium Agronomy and Crop Science Nucleoside Biotechnology
Zdroj:	Phytochemistry Letters. 36:68-72
ISSN:	1874-3900
Popis:	In order to validate the structure of a rarely reported naturally occurring nucleoside isolated from the broth of Penicillium sp. (NO. 64), practical syntheses of 2′-O-methyl-β- l -arabinosyluridine, 2′-O-methyl-α- l -arabinosyluridine, and 2′-O-methyl-β- l -uridine were accomplished. Comparing their nuclear magnetic resonance (NMR) spectra and physical data, its structure was reassigned as 2′-O-methyl-β- l -uridine instead of former reported 2′-O-methyl-β- l -arabinosyluridine.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4a0caa5a203718b848fc84b2557a5307 https://doi.org/10.1016/j.phytol.2020.01.018 Zobrazit plný text záznamu Full Text from ScienceDirect