A Pyrolytic Approach to 2-Hydroxy-7-methoxy-5-methyl-1-naphthoic Acid

Autor:	Roger F. C. Brown, Frank W. Eastwood, Julianna M. Horvath
Rok vydání:	1995
Předmět:	Green chemistry Reaction mechanism Flash vacuum pyrolysis Biocatalysis Chemistry Yield (chemistry) Enediyne Moiety General Chemistry Medicinal chemistry Catalysis
Zdroj:	Australian Journal of Chemistry. 48:1055
ISSN:	0004-9425
DOI:	10.1071/ch9951055
Popis:	Condensation of 4-methoxy-2,6-dimethylbenzaldehyde with Meldrum's acid, and flash vacuum pyrolysis of the condensation product (12) gave in almost quantitative yield 7-methoxy-5-methyl-2-naphthol (9). This naphthol is a precursor of the title 1-carboxylic acid (6), an intercalating moiety of enediyne and other antibiotics.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4a03058167291bcf65b7d12815a11c13 https://doi.org/10.1071/ch9951055 Zobrazit plný text záznamu