СУЧАСНІ АСПЕКТИ ДІАГНОСТИКИ ГАСТРОЕЗОФАГЕАЛЬНОЇ РЕФЛЮКСНОЇ ХВОРОБИ

Autor: T. V. Boiko
Rok vydání: 2017
Předmět:
Zdroj: Здобутки клінічної і експериментальної медицини.
ISSN: 2415-8836
1811-2471
DOI: 10.11603/1811-2471.2017.v0.i2.7748
Popis: SUMMARY. Gastroesophageal reflux disease is an extremely common disease caused by violation motor-evacuatory function of organs of gastroesophageal zone, characterized by spontaneous reproach of gastric or duodenal contents in esophagus which lead to defeat distal department with development inflammatory and erosive-ulcerous lesions. Among adults prevalence of gastroesophageal reflux disease is 40 %. The aim of the work – to analyze modern views of scientists and show general methods of diagnostic gastroesophageal reflux disease. In the diagnostics of gastroesophageal reflux disease we need to focus on recommendation of Monreal consentus whereby disease can be diagnosed in the presence of at least of 3 critters: typical symptoms of disease, instrumental confirmation presence of pathology gastroesophageal reflux in people with gastrophageal reflux disease symptoms, mucosal changes of esophagus, histology study biopsy. In accordance with IV Maastrihts consensus recommended to eradication Helicobacter pylori regardless a presence or absence of symptoms of gastroesophageal reflux disease in the presence of direct hits. Diagnosis of gastroesophageal reflux disease established on the basis clinical criterion if patients are concerned pyrosis more than 2 times a week for 3 month or more. For the diagnostic of gastroesophageal reflux disease we offеred omeprazole and alginate tests. Display for the esophagogastroduodenoscopy in patients with gastroesophageal reflux disease availability of symptoms (dysphagia, nausea, bleeding, weigth loss, inefficiency of frial treatment (negative omeprazole and alginate tests), long course of disease, more than 50 years. Esophagogastroduodenoscopy serve to identify or exclusion significant damage in some cases. With typical symptoms no meal to take before the esophagogastroduodenoscopy to make the esophagus for the diagnostics of eosinophily esophagitis. To quantify of influence acid on the esophagus evaluation between pyrosis and reflux episodes, use ph-metry in esophagus or impedance-metry for 24 hours. Esophagus impedance use in the patients with persistent symptoms of reflux, who respectively meet the standard therapy, to assess acid and non-acid reflux disease. To identify minimal lesions mucous of asophagus in patients with gastroesophageal reflux disease. Use chromoscopy, endoscopy with high quality and zoom, narrow spectral endoscopy. Conclusions. So, the main method of diagnostic gastroduodenal reflux disease is gastrofibroduodenoscopy. Modern endoscopstechnology make it possible to diagnose gastroesophageal reflux disease on early stage. Future prospects for further rescarch is to explore new methods of diagnostic, therapy and prevention gastroduodenal reflux disease.
Databáze: OpenAIRE
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