| Popis: |
Prosthetic joint infections are optimally treated with a 2-stage revision. However, because of frequent comorbid illness, the prosthesis cannot always be removed. When this is the case, long-term suppressive oral antibiotics are often given to prevent breakthrough infection; however, there is minimal data on this practice. We performed a retrospective case series of patients at our own institution and reviewed published case series on the topic. A systematic review was performed on the available data. The odds ratio for successful outcome in the pooled analysis was 1.3 (95% confidence interval, 0.6-3.1) in favor of suppressive antibiotics, but this difference was not significant. We conclude that, despite the common use of suppressive antibiotic therapy for retained prosthetic joints, there is insufficient data to demonstrate whether this practice reduces failure rates. |
