Genital association of human papillomavirus with Mycoplasma and Ureaplasma spp. in Mexican women with precancerous lesions
| Autor: | Adriana Contreras-Paredes, Alma Chavez-Blanco, Nancy Patricia Gómez-Crisóstomo, Eduardo Martínez-Abundis, Silvia Vazquez-Jimenez, Erick de la Cruz-Hernandez, Maria Lopez-Arias |
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| Rok vydání: | 2019 |
| Předmět: |
Dermatology
urologic and male genital diseases medicine.disease_cause law.invention 03 medical and health sciences Ureaplasma 0302 clinical medicine law Genotype medicine Pharmacology (medical) Sex organ Colonization 030212 general & internal medicine Human papillomavirus Polymerase chain reaction 0303 health sciences biology 030306 microbiology business.industry Public Health Environmental and Occupational Health Mycoplasma biology.organism_classification Virology female genital diseases and pregnancy complications Infectious Diseases Abnormal cervical cytology business |
| Zdroj: | International Journal of STD & AIDS. 30:969-977 |
| ISSN: | 1758-1052 0956-4624 |
| DOI: | 10.1177/0956462419855508 |
| Popis: | The genital colonization of certain Mycoplasma and Ureaplasma spp. has been associated with an increased the risk of acquisition and persistence of human papillomavirus. However, its association with high-risk human papillomavirus genotypes is not entirely clear, and the prevalence of such coinfections in cervical precancerous lesions has been poorly explored. Therefore, the aim of this study was to investigate the association of high-risk human papillomavirus with Mycoplasma and Ureaplasma spp. in 258 women recruited during their routine gynecological inspection at an outpatient clinic in Tabasco, Mexico. Among the Mycoplasma and Ureaplasma spp. evaluated in the present study, the highest peak of prevalence was attributed to Ureaplasma parvum (32.9%), followed by Mycoplasma hominis (14%), Ureaplasma urealyticum (6.6%), and Mycoplasma genitalium (0.8%). The overall prevalence rates of papillomavirus DNA and high-risk human papillomavirus were 25.6% and 17.1%, respectively. The overall association showed that M. hominis and U. urealyticum correlated significantly with high-risk human papillomavirus infection. According to the cytological results, the distribution of coinfection with high-risk human papillomavirus and U. urealyticum did not show significant differences with respect to severity of cervical lesions. Conversely, the association of high-risk human papillomavirus with M. hominis was more frequent in women with high-grade squamous intraepithelial lesions ( P = 0.037). |
| Databáze: | OpenAIRE |
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