Studies on Thiazolopyridines. Part 4: Synthesis of Hitherto Unknown 1,4-Bis(thiazolopyridine)benzene Derivatives

Autor:	Moustafa M. Khafagy, Ahmed A. El-Maghraby, Mohamed H. Helal, Gameel A. M. El-Hag Ali, Mohamed S. A. El-Gaby, Hassan A. Eyada
Rok vydání:	2003
Předmět:	Inorganic Chemistry chemistry.chemical_classification chemistry.chemical_compound chemistry Molar ratio Organic Chemistry Condensation Benzene derivatives Organic chemistry Benzene Spectral data Biochemistry Aldehyde
Zdroj:	Phosphorus, Sulfur, and Silicon and the Related Elements. 178:1681-1688
ISSN:	1563-5325 1042-6507
Popis:	2-Cyanomethyl-4-thiazolinone ( 1 ) was condensed with terephthalaldehyde ( 2 ) (2:1 molar ratio) and produced 1,4-bis(2-cyanomethyl-4,5-dihydro-5-methylidene-4-thiazolinone-5-yl) benzene ( 3 ). Treatment of compound ( 3 ) with benzylidenemalononitrile ( 4 ) (1:2 molar ratio) furnished the novel bisthiazolopyridines ( 6a-e ). Condensation of compound ( 1 ) with aromatic aldehyde yielded the benzylidene derivatives ( 7a-f ), which on treatment with compound ( 8 ) (2:1 molar ratio) afforded the novel bisthiazolopyridines ( 10a-f ). Structures of the synthesized compounds have been established by elemental analyses and spectral data.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::49e02a2f42ebe3c463d7f657e80d1c2c https://doi.org/10.1080/10426500307827 Zobrazit plný text záznamu