Increase in the negative charge of erythrocyte membrane proteins in hereditary neuromuscular diseases

Autor: Tagiev Af, Sitnikov Vf, Khrennikov VIu, Deev Ai
Rok vydání: 1990
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 110:1426-1428
ISSN: 1573-8221
0007-4888
DOI: 10.1007/bf00842308
Popis: The parameters of erythrocyte ghost protein's fluorophores by nitrate's anions were studied in patients with various hereditary myodystrophy. In all the groups under examination the share of fluorophores accessible to a quencher was close to 1. In erythrocyte membranes of healthy donors the relevant constant quenchering was about 17.3 +/- 1.9 M-1 while those of patients were decreased by 3.1 (Duchenne's myodystrophy) and by about 2.0 (other forms of primary and secondary progressive muscular dystrophies). The most probable reason for the decreasing constant of quenchering is the increase of negative charges on the erythrocyte membrane proteins.
Databáze: OpenAIRE