Estrogen Regulation of Protooncogene Expression

Autor: Lata Murthy, Connie Chiappetta, Salman M. Hyder, Claudia A. Orengo, John L. Kirkland, Tsu-Hui Lin, George M. Stancel, David S. Loose-Mitchell, Ulka Tipnis
Rok vydání: 1992
Předmět:
Zdroj: Hormonal Carcinogenesis ISBN: 9781461392101
DOI: 10.1007/978-1-4613-9208-8_25
Popis: Our basic approach to the problem of hormonal carcinogenesis has been to investigate the mechanisms by which physiologically relevant levels of estrogens regulate the growth and function of normal target tissues. This information is required to understand the mechanisms of carcinogenesis in hormone target tissues, the role of the hormone in these processes, and rational approaches to the prevent,ion and treatment of major human diseases such as prostate, endometrial, and breast cancer. The experimental system we have used for our studies is the immature rat uterus.
Databáze: OpenAIRE