Dietary zinc supplements do not enhance catch-up growth of rats during recovery from protein-zinc malnutrition when the diets are based on either isolated soybean protein or casein
| Autor: | Barbara J. Stoecker, Stephen R. Glore, John W. Erdman, Allen W. Knehans, Victoria L. Orth |
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| Rok vydání: | 1993 |
| Předmět: |
medicine.medical_specialty
Nutrition and Dietetics biology Endocrinology Diabetes and Metabolism Albumin Serum albumin chemistry.chemical_element Factorial experiment Zinc Bioavailability Endocrinology Human nutrition Animal science chemistry Casein Internal medicine biology.protein medicine Soy protein |
| Zdroj: | Nutrition Research. 13:1025-1037 |
| ISSN: | 0271-5317 |
| Popis: | Young male rats were fed a low-protein (LP) diet (3% albumin) with 9 ug Zn/g diet for 21 d which halted the growth process. Relative to baseline values (d O), the LP diet resulted in decreases of 19%, 47%, and 13% in serum albumin, serum zinc, and tibia zinc, respectively. Control rats were fed a balanced diet containing 15% albumin and 12 ug Zn/g for the same 21 d. The major objective of the study was to determine the efficacy of dietary zinc at and above the normal requirement (12 ug/g) to support catch-up growth after severe malnutrition. Following the 21 d LP or C periods, rats were fed for another 21 d with diets containing either 20% isolated soybean protein or 20% casein and supplemented with 1 of 3 levels of zinc ranging from 12 ug/g to 45 ug/g; a 2×2×3 factorial design was used. The rats recovering from protein malnutrition gained weight faster than the controls, but after 21 d the catch-up growth was still incomplete. Soybean protein, compared to casein, significantly depressed recovery of body weight, body length, and serum albumin. Dietary zinc supplementation of 36 ug/g was sufficient to replete both serum and tibia zinc but did not significantly improve catch-up growth in any of the tisues measured. |
| Databáze: | OpenAIRE |
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