Issues of spectrum and local sensitivity of E. coli in female patients with acute uncomplicated lower urinary tract infection – a review of M. Seitz study and own observations
| Autor: | Llc «Family Polyclinic », Moscow, Russia, D.G. Tsarichenko Tsarichenko, D.V. Platonova Platonova, M.S. Evdokimov Evdokimov, Yu L Demidko, A.N. Rossolovsky Rossolovsky, L.M. Rapoport Rapoport, L.G. Spivak Spivak, D.V. Enikeev Enikeev |
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| Rok vydání: | 2018 |
| Předmět: |
Drug
medicine.medical_specialty Microbiological culture biology business.industry medicine.drug_class media_common.quotation_subject Urinary system Antibiotics General Medicine Urine medicine.disease_cause biology.organism_classification Internal medicine Medicine Medical prescription business Escherichia coli Bacteria media_common |
| Zdroj: | Urologiia. :58-62 |
| ISSN: | 1728-2985 |
| Popis: | RELEVANCE Acute uncomplicated lower urinary tract infections (AULUTI) are one of the most common diseases in urological practice. The management of cystitis is commonly based on antibacterial therapy. Despite the high efficiency, inadequate prescription of antibiotics leads to an increase in microorganisms resistance. In light of these matters, the selection of antibacterial agents to which the sensitivity of bacteria is the highest is becoming increasingly challenging. AIM To estimate the spectrum and local sensitivity of E. coli in patients with AULUTI. MATERIALS AND METHODS The present study analyzed the results of bacterial culture sampled from 45 patients with AULUTI. The mean age of the patients was 44+/-17 years. All bacterial cultures were obtained in out-patient settings in the framework of a multicenter initiative study on the prevention of recurrent AULUTI with d-mannose. RESULTS Microbiological studies of the urine of patients with AULUTI revealed the growth of E. coli in concentrations ranging from 104 to 107 CFU/ml. Assessment of sensitivity demonstrated 100% sensitivity of Escherichia coli to fosfomycin trometamol. CONCLUSION According to the findings of microbiological studies, the patients with the AULUTI retain the highest sensitivity level of E.coli to phosphomycin trometamol, which allows it to be used as a first-line drug. |
| Databáze: | OpenAIRE |
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