Azotemia and Mortality among Babesia microti-Like Infected Dogs
| Autor: | J. J. Gestal, A. Sonia Olmeda, A. Tomas Camacho, F. Javier Guitian, Heidi K. Goethert, E. Pallas, Sam R. Telford, Andrew Spielman |
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| Rok vydání: | 2004 |
| Předmět: |
Creatinine
medicine.medical_specialty Proteinuria General Veterinary business.industry urologic and male genital diseases medicine.disease Gastroenterology Uremia Surgery chemistry.chemical_compound Hyperphosphatemia chemistry Internal medicine Case fatality rate medicine Azotemia Hypoalbuminemia medicine.symptom business Cause of death |
| Zdroj: | Journal of Veterinary Internal Medicine. 18:141-146 |
| ISSN: | 1939-1676 0891-6640 |
| DOI: | 10.1111/j.1939-1676.2004.tb00152.x |
| Popis: | Babesia microti-like piroplasms are a recently recognized cause of illness in dogs in northwest Spain. Our objective was to describe the clinical characteristics and investigate the risk factors for azotemia and death among 58 B microti-like infected dogs. Twenty-one of the 58 (36%) dogs were azotemic at the time that the infection was diagnosed. The case fatality rate during the following week was 22%. Dogs with azotemia at the time of diagnosis were 10 times (95% CI, 3.26-28.8) more likely to die during the following week. Azotemia was the main cause of death for B microti-like infected dogs (attributable fraction = 90%). Severe anemia was present in 45 of the 58 (78%) dogs. Azotemic dogs also presented with hyperphosphatemia, hypoalbuminemia, hypercholesterolemia, proteinuria, and high urine protein: creatinine ratios, suggesting a glomerular component to the disease. Age was the only factor significantly associated with the risk of azotemia (P = .042): on average, a 4-year age increase doubled the risk of an infected dog being azotemic. The only factor significantly associated with mortality was azotemia (P = .001). We concluded that B microti-like infection is associated with a high risk of azotemia and mortality. |
| Databáze: | OpenAIRE |
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