The Hardest Part
| Autor: | Uwe Raaz, Karin Mattern, Isabel N. Schellinger |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Gerontology
0303 health sciences business.industry Disease 030204 cardiovascular system & hematology medicine.disease 3. Good health 03 medical and health sciences 0302 clinical medicine Elderly population Arterial stiffness Medicine Vascular aging Healthy aging Cardiology and Cardiovascular Medicine business 030304 developmental biology |
| Zdroj: | Arteriosclerosis, Thrombosis, and Vascular Biology. 39:1301-1306 |
| ISSN: | 1524-4636 1079-5642 |
| DOI: | 10.1161/atvbaha.118.311578 |
| Popis: | Aging has a significant impact not only on every single individual but on society as a whole. Today, people throughout the world exhibit an extended lifespan. Therefore, it becomes increasingly important to develop novel concepts that encourage a modern understanding of the aging process. The concept of healthy aging shifts the perception of aging as a burden towards aging as an opportunity for an extended healthy phase in later life. Morbidity and mortality in the elderly population are greatly defined by a raise in the incidence and prevalence of cardiovascular diseases. Consequently, it is critical to identify risk factors and underlying mechanisms that render the aging (cardio)vascular system prone to disease. In this review, we focus on structural mechanisms of arterial stiffening as a major manifestation of vascular aging and its functional implications for the concept of healthy aging. |
| Databáze: | OpenAIRE |
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