Potentially Reversible Brachial Vasodilatation and Impaired Flow-mediated Reactivity in Acute Kawasaki Disease

Autor: Mio Koike, Yusuke Itagaki, Natsuko Hoshino, Tae Matsumura, Tetsuzo Tagawa, Tetsuya Sano
Rok vydání: 2003
Předmět:
Zdroj: Pediatric Research. 53:183-183
ISSN: 1530-0447
0031-3998
DOI: 10.1203/00006450-200301000-00178
Popis: It remains to be determined the nature and period of vascular endothelial damage by a systemic vasculitis in the acute phase of Kawasaki disease (KD). To elucidate the impact of systemic vasculitis of acute KD on peripheral arterial dimension and reactivity, using high-resolution ultrasound system (Toshiba SSA 380A system with 7.5MHz linear-array transducer) vasodilative response to reactive hyperemia of brachial artery was evaluated in 23 children with acute KD (1.3±1.0 months after onset), 10 in recovery phase (10±2.6 months) and 33 age- and sex- matched control subjects (C). The reactive hyperemia was obtained by the pneumatic tourniquet inflated on the forearm to 180mmHg for 3 minutes and released. Baseline diameters of brachial artery were significantly enlarged both in acute KD (2.8±0.35mm, p
Databáze: OpenAIRE