Pyrrolocoumarins. 1. Synthesis and Spectroscopic Investigation of 7-Oxo- and 1,2,7-Trioxo-1,2-dihydropyrano-[3,2-e]indole and Their Derivatives

Autor: M. I. Sikharulidze, T. E. Khoshtariya, L. T. Bochoidze, V. O. Ananiashvili, V. G. Turabelidze, N. T. Mirziashvili, M. G. Maisuradze, I. G. Abesadze, T. O. Dzhashi, L. N. Kurkovskaya, K. T. Batsikadze
Rok vydání: 2005
Předmět:
Zdroj: Chemistry of Heterocyclic Compounds. 41:208-215
ISSN: 1573-8353
0009-3122
Popis: A preparative route is proposed for the synthesis of the novel heterocyclic systems 7-oxo- and 1,2,7-trioxo-1,2-dihydropyrano[3,2-e]indole using classical Fischer and Sandmeyer methods respectively. We have studied various conditions for cyclization of the starting coumarin 6-isonitrosoacetamide and the methyl or ethyl pyruvate 6-coumarinylhydrazones. The syn- and anti-form ratio of the latter and the structure of all of the synthesized compounds were determined using spectroscopic data analysis.
Databáze: OpenAIRE