Hepatitis E: The Commonest Viral Zoonosis Worldwide?

Autor: Harry R. Dalton, Jacques Izopet, Nassim Kamar, R. Bendall, Malcolm Banks
Rok vydání: 2014
Předmět:
Zdroj: Zoonoses-Infections Affecting Humans and Animals ISBN: 9789401794565
Popis: Until recently, HEV was thought not to occur in developed countries. It is now clear that locally acquired HEV is common in many developed countries. HEV infection acquired in these areas differs from that in developing countries in a number of important aspects: it is caused by genotype 3 (and 4 in China and Japan); it mainly affects middle-aged/elderly males; it is zoonotic with a porcine primary host. Pig herds worldwide are infected with HEV genotype 3 and HEV has been found in the human food chain in a number of developed countries. However, the route of transmission is not fully understood, since most cases are not obviously associated with pigs/pig products. HEV can be transmitted by blood transfusion and surprisingly high numbers of asymptomatic blood donors are viraemic at the time of donation.
Databáze: OpenAIRE