Trifluoroacetylation of Anilines with Ethyl Trifluoropyruvate Mediated by Copper(I) Chloride

Autor:	Zhang Jieyu, Guobing Yan, Qiumin Ke, Jian Yu, Jiaying Chen
Rok vydání:	2019
Předmět:	chemistry.chemical_compound Ethyl trifluoropyruvate chemistry 010405 organic chemistry Organic Chemistry Organic chemistry Copper(I) chloride 010402 general chemistry 01 natural sciences Biochemistry 0104 chemical sciences
Zdroj:	Letters in Organic Chemistry. 16:860-864
ISSN:	1570-1786
DOI:	10.2174/1570178616666190311162001
Popis:	A novel copper(I)-mediated trifluoroacetylation of anilines with ethyl trifluoropyruvate as a trifluoroacetylating reagent has been developed. Although this protocol could provide good yields in most cases, the reaction exhibited the obvious electronic and steric effects of substituents. The trace amount of products was only obtained for the substrates with ortho-substituted or electron-deficient groups.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::491a02ca2a7d337f64181a8477fd2fde https://doi.org/10.2174/1570178616666190311162001 Zobrazit plný text záznamu