Is the Morning Peak of Acute Myocardial Infarction’s Onset Due to Sleep-Related Breathing Disorders?

Autor:	F. Bertin, Victor Aboyans, Claude Cassat, François Tabaraud, Philippe Lacroix, Philippe Tapie, Francis Pesteil, Patrice Virot, Marc Laskar
Rok vydání:	2000
Předmět:	Sleep disorder business.industry Respiratory disease Apnea Hemodynamics Sleep apnea medicine.disease Anesthesia medicine Pharmacology (medical) Myocardial infarction Circadian rhythm medicine.symptom Cardiology and Cardiovascular Medicine business Morning
Zdroj:	Cardiology. 94:188-192
ISSN:	1421-9751 0008-6312
DOI:	10.1159/000047315
Popis:	Many studies have shown that the risk of experiencing a myocardial infarction (MI) is increased during the first hours of the morning. Sleep apnea syndrome (SAS) is associated with an enhanced adrenergic activity, prolonged a few hours after awakening. We aimed at assessing whether sleep breathing disorders could be a culprit for the morning excess rate of MI. We studied 40 middle-aged men admitted for an acute MI. An overnight polysomnographic study was performed 37.4 ± 9.4 days after the MI. The prevalence of SAS was high (30%). The prevalence of SAS was significantly higher in patients with the MI onset during the morning. The circadian pattern was significantly different in patients with or without SAS: those with SAS presented an important peak of MI onset during the period between 06.00 and 11.59 h. None of them had their MI during the period between 24.00 and 05.59 h. This different nyctohemeral pattern underlines the potential role of sleep breathing disorders as a trigger of MI.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::490723241d11a27c153720cfdcb43d04 https://doi.org/10.1159/000047315 Zobrazit plný text záznamu