Adaptation to intermittent hypoxia-hyperoxia improves cognitive performance and exercise tolerance in the elderly

Autor: Rudolf Likar, U Bayer, Susanne Demschar, Oleg S. Glazachev, Martin Burtscher, Brigitte Trummer, Georg Pinter, Haro Stettner, W Kofler, Stefan Neuwersch
Rok vydání: 2017
Předmět:
Zdroj: Advances in Gerontology. 7:214-220
ISSN: 2079-0589
2079-0570
DOI: 10.1134/s2079057017030031
Popis: For improvements in exercise tolerance and cognitive function in geriatric patients Multimodal training programs (MTP) are used as combination of physiotherapy, occupational therapy and cardiovascular training. Intermittent Hypoxic-Hyperoxic Training (IHHT), a modified type of intermittent hypoxic training (IHT) is proposed to be included in MTP to elicit more pronounced beneficial effects in exercise tolerance and cognitive functions of geriatric patients likely by an additional pathway than a single MTP. Thirty four patients of the Geriatric Day Clinic aged between 64 and 92 years participated in the placebo controlled clinical trial. They were randomly assigned to receive MTP plus IHHT (experimental group - EG) or MTP plus placebo-breathing through a machine face mask (control group - CG) in a double blind fashion. Before and after the interventions course cognitive performance was assessed by the Dementia-Detection-Test (DemTect) and the Clock-Drawing-Test (CDT), and functional exercise capacity - by the total distance of 6-Minute-Walk-Test (6MWT). After IHHT combined with MTP cognitive performance (DemTect) increased significantly when compared to NG (+16,7 % vs. +0,39 %, p
Databáze: OpenAIRE