Cystatin C as a biomarker of acute kidney injury in sick neonates
| Autor: | Iqra Khan, Sweta Kumari, Raksha Gupta, Jyoti Bagla |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Creatinine Neonatal intensive care unit biology Respiratory distress business.industry General Engineering Acute kidney injury medicine.disease Gastroenterology Perinatal asphyxia Sepsis chemistry.chemical_compound chemistry Cystatin C Internal medicine medicine biology.protein Risk factor business |
| Zdroj: | Asian Journal of Pediatric Nephrology. 3:10 |
| ISSN: | 2589-9309 |
| DOI: | 10.4103/ajpn.ajpn_29_19 |
| Popis: | Objective: This study was planned to study serum cystatin C (CysC) levels in sick neonates admitted in neonatal intensive care unit (NICU) with predisposing risk factor(s) for development of acute kidney injury (AKI). We evaluated serum levels of CysC and creatinine in sick neonates. Methods: Ninety-four sick neonates with prematurity, sepsis, respiratory distress, and/or perinatal asphyxia requiring NICU admission were enrolled. Serum levels of creatinine and CysC were measured on day 3 of life. Results: Serum levels of both cystatin C and creatinine were significantly elevated in neonates who developed AKI versus those who did not (CysC: 2.18 ± 0.59 vs. 1.91 ± 0.47 mg/dl, P = 0.04; creatinine: 1.68 ± 0.75 vs. 0.89 ± 0.40, P |
| Databáze: | OpenAIRE |
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