Steroid-responsive encephalopathy associated with thyroiditis: A diagnostic challenge

Autor: Muhammad Tayyeb, Abdulaziz Zafar, Rubab Fatima Malik, Muhammad B Jamshaid, Phool Iqbal, Aamir Shahzad
Rok vydání: 2021
Předmět:
Zdroj: Libyan Journal of Medical Sciences. 5:36
ISSN: 2588-9044
DOI: 10.4103/ljms.ljms_86_20
Popis: steroid responsive encephalopathy associated with autoimmune thyroiditis (SREAT) is an autoimmune entity with a strong association with elevated antithyroid antibodies. It is a rare cause of encephalopathy and is usually a diagnosis of exclusion. Responsive to corticosteroids is required to make the diagnosis. Herein, we report a male patient presented with recurrent convulsive episodes not controlled well by anticonvulsant drugs and had drops in Glasgow coma scale (GCS). After unremarkable of extensive investigations, Hashimoto's encephalitis was suspected and antithyroid peroxidase antibodies test turned out to be positive, while thyroid function tests were normal and the diagnosis of steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT) was made. He received a course of intravenous methylprednisolone for 5 days and responded very well to therapy, with an improvement of his GCS to 15/15.
Databáze: OpenAIRE