Aripiprazole and Dehydro-Aripiprazole Solid Solutions: Crystalline Combinations of Drug and Active Metabolite in Tailored Compositions

Autor: Mark A. Oliveira, Tarek A. Zeidan, Jacob T. Trotta, Magali B. Hickey, Orn Almarsson, Renato A. Chiarella, Pranoti A. Tilak, Julius F. Remenar, Bruce M. Foxman
Rok vydání: 2020
Předmět:
Zdroj: Crystal Growth & Design. 20:3944-3956
ISSN: 1528-7505
1528-7483
DOI: 10.1021/acs.cgd.0c00263
Popis: Solid solutions of aripiprazole (APZ) and its active metabolite, dehydro-aripiprazole (dAPZ), have been prepared as free form (neat or nonsolvated), hydrated, or alcohol- solvated modifications wit...
Databáze: OpenAIRE