Aripiprazole and Dehydro-Aripiprazole Solid Solutions: Crystalline Combinations of Drug and Active Metabolite in Tailored Compositions
Autor: | Mark A. Oliveira, Tarek A. Zeidan, Jacob T. Trotta, Magali B. Hickey, Orn Almarsson, Renato A. Chiarella, Pranoti A. Tilak, Julius F. Remenar, Bruce M. Foxman |
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Rok vydání: | 2020 |
Předmět: |
Drug
010405 organic chemistry media_common.quotation_subject Alcohol General Chemistry 010402 general chemistry Condensed Matter Physics 01 natural sciences Combinatorial chemistry 0104 chemical sciences chemistry.chemical_compound chemistry medicine General Materials Science Free form Aripiprazole Active metabolite Solid solution media_common medicine.drug |
Zdroj: | Crystal Growth & Design. 20:3944-3956 |
ISSN: | 1528-7505 1528-7483 |
DOI: | 10.1021/acs.cgd.0c00263 |
Popis: | Solid solutions of aripiprazole (APZ) and its active metabolite, dehydro-aripiprazole (dAPZ), have been prepared as free form (neat or nonsolvated), hydrated, or alcohol- solvated modifications wit... |
Databáze: | OpenAIRE |
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