Quantitative determination of podophyllotoxin and related compounds inpodophyllum species by reverse phase high performance liquid chromatography
| Autor: | Jairo Kenupp Bastos, Charles L. Burandt, Wlodzimierz J. Kopycki, James D. McChesney, N. P. Dhammika Nanayakkara |
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| Rok vydání: | 1995 |
| Předmět: |
Chromatography
biology Chemistry Podophyllum Plant Science General Medicine biology.organism_classification Biochemistry High-performance liquid chromatography Quantitative determination Analytical Chemistry chemistry.chemical_compound Podophyllotoxin Podophyllotoxin derivatives Epipodophyllotoxin Complementary and alternative medicine Phase (matter) Drug Discovery medicine Molecular Medicine Gradient elution Food Science medicine.drug |
| Zdroj: | Phytochemical Analysis. 6:101-105 |
| ISSN: | 1099-1565 0958-0344 |
| DOI: | 10.1002/pca.2800060207 |
| Popis: | A rapid sensitive and reliable reverse phase high performance liquid chromatography method was developed using a Taxsilr column and gradient elution for the routine determination of podophyllotoxin and six related compounds, epipodophyllotoxin, α-peltatin, β-peltatin, 4′-demethylpodophyllotoxin, podophyllotoxin-4-O-glycoside, and 1,2,3,4-dehydrodesoxypodophyllotoxin in Podophyllum extracts. The elaborated method gave well resolved peaks for these compounds with good detection response and linearity in the range 25–450 ng. |
| Databáze: | OpenAIRE |
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