Rat Blood Leukocytes after Intravenous Injection of Magnetoliposomes on the Basis of Nanomagnetite

Autor: N. M. Shevtsova, E. A. Gereng, A. A. Ivanov, R. M. Takhauov, I. V. Mil’to, V. V. Ivanova, O. N. Serebryakova, I. V. Sukhodolo
Rok vydání: 2021
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 171:774-777
ISSN: 1573-8221
0007-4888
DOI: 10.1007/s10517-021-05314-0
Popis: The structure of blood neutrophils, eosinophils, monocytes, and lymphocytes and differential white blood count in adult rats were studied over 120 days after a single intravenous injection of magnetoliposomes based on nanomagnetite. Magnetoliposomes had no effect on the structure of neutrophils, eosinophils, monocytes, and lymphocytes. At the same time, injection of a suspension of magnetoliposomes based on magnetite nanoparticles led to a decrease in lymphocyte count and an increase in the count of monocytes and band and segmented neutrophils in the blood. These changes were transient and the parameters returned to normal by day 40-60 after injection.
Databáze: OpenAIRE