Base-Catalyzed Borylation/B–O Elimination of Propynols and B2pin2 Delivering Tetrasubstituted Alkenylboronates

Autor:	Jianxiang Yan, Haohua Chen, Qiuling Song, Yu Lan, Zhijie Kuang, Kai Yang
Rok vydání:	2018
Předmět:	010405 organic chemistry Organic Chemistry 010402 general chemistry 01 natural sciences Biochemistry Combinatorial chemistry Borylation 0104 chemical sciences Catalysis chemistry.chemical_compound chemistry Organic synthesis Physical and Theoretical Chemistry Base (exponentiation)
Zdroj:	Organic Letters. 20:5153-5157
ISSN:	1523-7052 1523-7060
Popis:	An efficient approach to tetrasubstituted alkenylboronates via a cascade borylation/B–O elimination of propynols and B2pin2 was disclosed. A series of tetrasubstituted alkenylboronates were readily furnished with this strategy in good yields, with further transformations leading to tetrasubstituted alkenes and β-diketones demonstrating the synthetic potential of the alkenylboronates constructed by this strategy as versatile intermediates in organic synthesis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::48cffef68c3d6fe98406bfdd03016071 https://doi.org/10.1021/acs.orglett.8b02077 Zobrazit plný text záznamu