Detection and Related Research of Serum Levels of IL-2, IL-6, IL-8 and ET in Patients with Hyperthyroidism
| Autor: | Wang Cuicui, Xu Qian, Li Hongyan, Hou Zhenjiang, Zhang Jingyu, Cao Tingting |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
endocrine system
medicine.medical_specialty Triiodothyronine endocrine system diseases biology business.industry Organic Chemistry Biochemistry Pathogenesis Endocrinology Thyroid-stimulating hormone Internal medicine biology.protein medicine In patient Interleukin 8 Thyroid function Interleukin 6 Endothelin receptor business hormones hormone substitutes and hormone antagonists |
| Zdroj: | Science Journal of Public Health. 8:177 |
| ISSN: | 2328-7942 |
| DOI: | 10.11648/j.sjph.20200806.14 |
| Popis: | Objective: To discuss the changes of serum levels of IL-2, IL-6, IL-8 and ET in patients with hyperthyroidism, and to analyze the correlation between them and thyroid function indexes, and to find more objective indexes for the diagnosis, treatment and prevention of hyperthyroidism. Methods: 251 patients with hyperthyroidism (Study Group) and 130 healthy persons (control group) were selected. Five indexes of serum thyroid function: serum free triiodothyronine (FT3), total triiodothyronine (TT3), serum free thyroxine (FT4), total thyroxine (TT4) and thyroid stimulating hormone (TSH) were measured by electrochemiluminescence. The levels of seruminterleukin-2 (IL-2), interleukin-6 (IL-6), interleukin-8 (IL-8) were detected by ELISA double antibody sandwich method, and the level of endothelin (ET) was measured by enzyme linked immunosorbent assay. Results: The level of IL-2 in study group was significantly lower (P |
| Databáze: | OpenAIRE |
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