Evaluation of the Significance of MRI in the Prenatal Diagnosis of Neural Tube Defects

Autor: A. Tenev, M. J. Kingsley-Godwin, K. Velkova, Magdalena Stoeva, V. Belovezhdov, E. Uchikova
Rok vydání: 2021
Předmět:
Zdroj: Journal of Medical and Biological Engineering. 41:881-887
ISSN: 2199-4757
1609-0985
DOI: 10.1007/s40846-021-00657-5
Popis: Congenital anomalies, also known as birth defects have been the primary focus of a number of studies globally. Our primary objective is to evaluate the significance of MRI in the prenatal diagnosis of congenital central nervous system (CNS) anomalies and explore the role of autopsy techniques in the postnatal phase as a verification tool. Additionally, we are focused on proving the MRI-specific diagnostic capabilities in comparison to the current gold standard based on autopsy. The study is based on a thorough analysis of incidences of congenital CNS anomalies in four women and their foetuses. Primary in-vivo MRI diagnostics and subsequent verification via autopsy (postmortem) have been performed. We described the foetal CNS anomalies based on MRI diagnostics and additionally verified the results by autopsy to confirm the findings and improve the services offered to patients and their families. The findings of the study confirmed the role of the MRI as a reliable tool for unequivocal diagnosis of congenital CNS anomalies and malformations.
Databáze: OpenAIRE
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