Automated Rapid Assessment of Surfactant and Fetal Lung Maturity
Autor: | Steven J. Zibrat, Atef H. Moawad, John A. Holt, Diane F. Ryan, Carol M. Cooper, John C. Russell |
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Rok vydání: | 1990 |
Předmět: |
medicine.medical_specialty
Pathology Lung Amniotic fluid Respiratory distress business.industry Biochemistry (medical) Clinical Biochemistry Albumin Gastroenterology medicine.anatomical_structure Pulmonary surfactant Fetal lung maturity Positive predicative value Internal medicine Conventional PCI medicine business |
Zdroj: | Laboratory Medicine. 21:359-366 |
ISSN: | 1943-7730 0007-5027 |
DOI: | 10.1093/labmed/21.6.359 |
Popis: | This study reports predictions for clinical respiratory distress syndrome (RDS) by means of a rapid test for fetal lung maturity based on fluorescence polarization of a dye (PCI 6) that partitions between surfactant and albumin in amniotic fluid. The test is completed in approximately 30 minutes and requires collection of a specimen volume of only 0.5 mL amniotic fluid. Results are reported as mg surfactantlg albumin (SIA value) equivalence. Ninety-three infants were delivered within 2 days of a collection of amniotic fluid and were followed up for the presence or absence of symptoms consistent with RDS. Ten infants, two of whom had anomalies, developed RDS. With a threshold of |
Databáze: | OpenAIRE |
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