Automated Rapid Assessment of Surfactant and Fetal Lung Maturity

Autor: Steven J. Zibrat, Atef H. Moawad, John A. Holt, Diane F. Ryan, Carol M. Cooper, John C. Russell
Rok vydání: 1990
Předmět:
Zdroj: Laboratory Medicine. 21:359-366
ISSN: 1943-7730
0007-5027
DOI: 10.1093/labmed/21.6.359
Popis: This study reports predictions for clinical respiratory distress syndrome (RDS) by means of a rapid test for fetal lung maturity based on fluorescence polarization of a dye (PCI 6) that partitions between surfactant and albumin in amniotic fluid. The test is completed in approximately 30 minutes and requires collection of a specimen volume of only 0.5 mL amniotic fluid. Results are reported as mg surfactantlg albumin (SIA value) equivalence. Ninety-three infants were delivered within 2 days of a collection of amniotic fluid and were followed up for the presence or absence of symptoms consistent with RDS. Ten infants, two of whom had anomalies, developed RDS. With a threshold of
Databáze: OpenAIRE