Radical homologation of d -gluconic acid: highly diastereoselective synthesis of d - gluco -KDO derivatives

Autor:	Mireille Le Hyaric, Joseph Cs. Jaszberenyi, Tetsuro Shinada, Wansheng Liu, Mauro V. De Almeida, Hélio F. Dos Santos, Derek H. R. Barton
Rok vydání:	2001
Předmět:	Stereochemistry Chemistry Radical Organic Chemistry Drug Discovery D-gluconic acid Organic chemistry Biochemistry
Zdroj:	Tetrahedron. 57:8767-8771
ISSN:	0040-4020
DOI:	10.1016/s0040-4020(01)00865-1
Popis:	d -glucono 1,5-lactone was converted to O-protected d -gluconic acids. The latter were transformed to gluco-KDO derivatives using Barton ester-based radical chemistry with high diastereoselectivity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::48920531fb2e28df3912de5349b88685 https://doi.org/10.1016/s0040-4020(01)00865-1 Zobrazit plný text záznamu Full Text from ScienceDirect