260 Early impairment of left ventricular diastolic function in patients with non-end stage idiopathic pulmonary fibrosis
| Autor: | Theodoros D. Karamitsos, P. Argiropoulou, Georgia Pitsiou, Haralampos Karvounis, Georgios Giannakoulas, Georgios E. Parharidis, Christodoulos Papadopoulos, Emmanuela G. Dalamaga |
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| Rok vydání: | 2006 |
| Předmět: |
medicine.medical_specialty
business.industry Diastole General Medicine medicine.disease Muscle hypertrophy Idiopathic pulmonary fibrosis Internal medicine Ventricular relaxation cardiovascular system medicine Cardiology Radiology Nuclear Medicine and imaging Diastolic function In patient cardiovascular diseases Stage (cooking) Cardiology and Cardiovascular Medicine business Ventricular filling |
| Zdroj: | European Journal of Echocardiography. 7:S29-S29 |
| ISSN: | 1525-2167 |
| DOI: | 10.1016/s1525-2167(06)60110-8 |
| Popis: | s S29 Eur J Echocardiography Abstracts Supplement, December 2006 diastolic function and clinical status between patients with asymmetrical apical and septal HCM. Methods: Forty HCM, 25 men, mean age 58±19 years, 10 apicals (AHCM), 16 obstructive asymmetrical septals (OAS) and 14 non-obstructive asymmetrical septals (NOAS) were studied. NYHA I: 70%, II: 22% and III 8%. Diastolic function was studied, with assessment of mitral patterns and pulmonary veins, and estimation of left ventricular filling pressures (LVFP) by the mitral E (E) and tissue E (E’) ratio. Results: 80% of patients with AHCM had normal diastolic function assessed by all the echocardiographic parameters. In the OAS group, no patient had normal diastolic function, and in the NOAS group only 35% had completely normal diastolic function. The AHCM group had significantly lower left ventricular filling pressures and higher tissue E velocities than the other groups (AHCM E/E’: 10, vs 17 in OAS vs 13 in NOAS and AHCM E’: 8 cm/sec vs 5.2 in OAS and 6.5 in NOAS. Regarding presence of symptoms, only 20% of AHCM had symptoms unlike the other groups which exceeded 40%. Conclusion: AHCM presents lesser diastolic function involvement than asymmetrical septal HCM. These data support the concept that apical hypertrophy has a lesser influence on ventricular relaxation than hypertrophy located in other segments. |
| Databáze: | OpenAIRE |
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