A Novel Approach That May Explain the Role of Staphylococcus aureus, Polycations, Neutrophils Pro-Inflammatory Agonists and the Bacteriolysis and Auto Immune Phenomena as Possible Major Events in the Pathogenesis of Atopic Dermatitis: A Working Hypothesis
| Autor: | Erez Koren, Isaac Ginsburg |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0303 health sciences
030306 microbiology business.industry Inflammation Atopic dermatitis Working hypothesis Auto immune medicine.disease medicine.disease_cause Rash Proinflammatory cytokine Pathogenesis 03 medical and health sciences Staphylococcus aureus Immunology medicine medicine.symptom business 030304 developmental biology |
| Zdroj: | Journal of Clinical & Experimental Dermatology Research. 10 |
| Popis: | The aim of the present short communication is to shed a novel light on the auto immune disorder atopic dermatitis by discussing the possible role played by the plethora of toxic agents released by Staphylococcus aureus which can act in a tight synergism with neutrophils derived cationic polyelectrolytes as related to the pathogenesis of atopic dermatitis (AD). This disorder results in inflammation of the skin characterized by itchiness, red skin, a rash, by the accumulations of large numbers of Staphylococcus aureus their toxins and proinflammatory agents secreted by migrating neutrophiles are considered the main cause of AD pathogenicity. |
| Databáze: | OpenAIRE |
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