A novel chemical reactor suited for studies of biophysical chemistry: Construction and evaluation of a selected ion flow tube utilizing an electrospray ion source and a triple quadrupole detection system
| Autor: | S. Feil, Michael J. Y. Jarvis, Vladimir Baranov, Diethard K. Bohme, Gregory K. Koyanagi, Janna Anichina, Scott D. Tanner |
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| Rok vydání: | 2007 |
| Předmět: |
Electrospray
Chemistry Electrospray ionization Selected reaction monitoring Analytical chemistry Extractive electrospray ionization Condensed Matter Physics Mass spectrometry Ion source Triple quadrupole mass spectrometer Physics::Chemical Physics Physical and Theoretical Chemistry Nuclear Experiment Instrumentation Spectroscopy Ambient ionization |
| Zdroj: | International Journal of Mass Spectrometry. 265:295-301 |
| ISSN: | 1387-3806 |
| DOI: | 10.1016/j.ijms.2007.02.049 |
| Popis: | A novel electrospray ion source/selected ion flow tube/triple quadrupole detector mass spectrometer has been constructed for the study of the kinetics and product distributions of reactions of a diverse array of electrosprayed ions reacting with neutral molecules. The electrospray source provides a near-universal source for ions of biological and other interests. The operation of the instrument is demonstrated with a selection of reactivity and kinetic measurements and threshold collision-induced dissociation determinations. Reactions investigated include H/D exchange between protonated bradykinin and deuterated ammonia, the protonation of the oligo-nucleotide anion [AGTCTG − 5H + ] 5− with HBr, the ozonolysis of Ca 2+ , the reaction of protonated phthalic anhydride with dimethyl disulfide, and the Argon collision-induced dissociation of Ba(C6H6) 2+ . |
| Databáze: | OpenAIRE |
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