Malignome nach Nierentransplantation: Stellenwert eines jährlichen radiologischen Screeningprogramms
| Autor: | Banyai S, Turetschek K, Thomas H. Helbich, Gerhard H. Mostbeck, Franz Kainberger, Gertraud Heinz-Peer |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Kidney
medicine.medical_specialty business.industry medicine.medical_treatment Urology urologic and male genital diseases medicine.disease Asymptomatic Surgery Transplantation Cystic kidney disease medicine.anatomical_structure medicine Carcinoma Radiology Nuclear Medicine and imaging medicine.symptom business Prospective cohort study Kidney transplantation Dialysis |
| Zdroj: | RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren. 163:250-255 |
| ISSN: | 1438-9010 1438-9029 |
| Popis: | PURPOSE To evaluate the prevalence of malignant neoplasms after renal transplantation by means of a radiological screening programme and to determine the role of some clinical and demographic parameters concerning pathogenesis of these malignancies. MATERIAL AND METHODS Between November 1992 and June 1994 in a prospective study 504 consecutive renal allograft recipients (331 m, 173 f) aged 51 +/- 13 years underwent routine abdominal ultrasound examinations including the renal transplant and p.a. and lateral chest x-rays once a year. RESULTS This screening programme revealed 11 malignant neoplasms in 11 patients (2.2%). We detected 6 renal cell carcinomas (RCC) in the patient's native kidneys, two RCCs in two renal allografts, two non-Hodgkin-lymphomas in the liver and the renal allograft, respectively, and one ovarial carcinoma. Patients with renal cell carcinomas in the native kidneys were significantly older than allograft recipients without tumors. The presence of acquired cystic kidney disease (ACKD) seems to be an additional risk for the development of RCC. There were no significant differences in the time on dialysis, the time with functional renal allograft, and the immunosuppressive therapy. CONCLUSION Yearly abdominal ultrasound screening including the renal allograft is a valuable tool for the early detection of neoplasms in asymptomatic renal allograft recipients. However, routine yearly chest x-rays should not be performed in renal allograft recipients without preexisting tumours. |
| Databáze: | OpenAIRE |
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