Partial Pressure of Oxygen in Arterial Blood of Patients: Description of an Aerotonometer Method

Autor:	Ford K. Hick
Rok vydání:	1936
Předmět:	Blood pressure Chemistry Continuous noninvasive arterial pressure Direct method Thermodynamics Arterial blood Oxygen–haemoglobin dissociation curve Partial pressure General Biochemistry Genetics and Molecular Biology Oxygen saturation (medicine) Oxygen tension
Zdroj:	Experimental Biology and Medicine. 33:582-587
ISSN:	1535-3699 1535-3702
DOI:	10.3181/00379727-33-8460c
Popis:	The partial pressure of oxygen in the arterial blood has been measured indirectly by interpolation of O2 content on the oxyhemoglobin dissociation curve, and by estimation of solubilities of CO and O2 in the subject's blood (Haldane), and directly by aerotonometry. The latter method has been used by Krogh1 and by Barcroft and Nagahashi.2 In this method of the latter authors some difficulty is experienced in keeping the equilibration pressure constant and in securing repeated samples of the small gas bubble for analysis. The present method avoids these two difficulties.It has been customary to study anoxemic patients by determining the oxygen saturation of the arterial blood and to assume that the oxyhemoglobin dissociation curve is shifted only as changes in the pH take place. Barcroft3 has studied the partial pressure of oxygen in a few such cases. However, it seemed that a simple, direct method for measurement of oxygen tension would permit a more exhaustive exploration of this field.About 20 mil. of bl...
Databáze:	OpenAIRE
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