Intrahepatic cholestasis of pregnancy
| Autor: | Gheorghe Peltecu, Anca Marina Ciobanu, Ana Maria Scutelnicu, Pharmacy, Bucharest, Romania, Radu Botezatu, Corina Gică, Brînduşa Ana Cimpoca-Raptis, Anca Maria Panaitescu, Nicolae Gică |
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| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Romanian Journal of Medical Practice. 16:50-55 |
| ISSN: | 2069-6108 1842-8258 |
| DOI: | 10.37897/rjmp.2021.s3.11 |
| Popis: | Intrahepatic cholestasis of pregnancy is the most common liver disease during pregnancy. The main features are maternal pruritus, in the absence of a rash, and raised serum bile acids. Intrahepatic cholestasis of pregnancy is associated with an increased risk of adverse perinatal outcomes, including preterm birth, meconium-stained amniotic fluid, fetal asphyxia with neonatal unit admission or even stillbirth. The main treatment option is ursodeoxycholic acid. We review the etiology, diagnosis, adverse pregnancy outcomes, focusing especially on management of this intriguing condition. |
| Databáze: | OpenAIRE |
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