A Convenient Microwave-Assisted Propylphosphonic Anhydride (T3P®) Mediated One-Pot Pyrazolone Synthesis

Autor: Matthieu Desroses, Sylvain A. Jacques, Martin Scobie, Thomas Helleday, Marie-Caroline Jacques-Cordonnier, Sabin Llona-Minguez, Tobias Koolmeister
Rok vydání: 2013
Předmět:
Zdroj: European Journal of Organic Chemistry. 2013:5879-5885
ISSN: 1434-193X
Popis: This paper describes a facile, efficient, and clean synthesis of various pyrazolones by employing T3P® as a catalyst and performing the reaction under microwave irradiation. This two-step, one-pot reaction proceeded readily and tolerated a variety of functional groups. A wide range of pyrazolone derivatives were obtained in good to excellent yields.
Databáze: OpenAIRE
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